In an NDC number, which segment identifies the packaging?

• A. The first five digits identify the drug manufacturer.
• B. The middle four digits identify the drug product.
• C. The last two digits identify the packaging.
• D. The entire 11-digit sequence identifies the substance.

Answer: (C)

An NDC is organized into three parts that identify who makes the product, what the product is, and how it is packaged. The last two digits specifically denote the packaging, meaning the package size or type of the product. This separation lets pharmacists and insurers know not only which drug it is, but exactly which package variant is being referenced.

So, the first segment points to the manufacturer, the middle segment identifies the drug product (including strength and dosage form), and the final two digits identify the packaging. The entire 11-digit code encodes both the product and its packaging, not just the substance alone.